Understanding Adenomyosis and How It Affects Fertility

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Dr Kelly Loi
Dr Kelly Loi

Senior Consultant Obstetrician & Gynaecologist

Medical Director & Clinical Governance Officer (CGO) of Monash IVF Singapore

Medical Director of Health & Fertility Centre for Women

Adenomyosis can affect fertility by altering the structure and function of the uterus, which may make embryo implantation more difficult. However, not all women with adenomyosis experience infertility, and many are still able to conceive naturally or with medical support. Early diagnosis and personalised care can help improve reproductive outcomes.

Key Takeaways

  • Adenomyosis is a condition where uterine lining tissue grows into the muscle wall
  • It can affect fertility by disrupting implantation
  • Symptoms include heavy periods, pain, and pelvic pressure
  • Diagnosis typically involves ultrasound or MRI
  • Many women can still conceive with appropriate care

What Is Adenomyosis?

Adenomyosis is a gynaecological condition in which tissue similar to the lining of the uterus (endometrium) grows into the muscular wall of the uterus. This tissue thickens and breaks down during each menstrual cycle, which can cause the uterus to become enlarged and inflamed.

Common symptoms include heavy or prolonged menstrual bleeding, severe menstrual cramps, and chronic pelvic pain. Some women experience mild symptoms or none at all.

Adenomyosis most often affects women in their 30s and 40s, although it can occur earlier. Because its symptoms overlap with conditions such as fibroids and endometriosis, it may not always be immediately recognised without imaging tests like pelvic ultrasound or MRI.

Can Adenomyosis Affect Fertility?

Adenomyosis can affect fertility by changing the uterine environment in ways that may interfere with conception and early pregnancy. The degree of impact varies depending on the severity of the condition and individual factors.

Some women with adenomyosis conceive without difficulty, while others may experience challenges, particularly when undergoing fertility treatments such as in-vitro fertilisation (IVF).

How Adenomyosis May Affect Fertility

Adenomyosis may influence fertility through several mechanisms:

  • Altered uterine structure: Changes in the uterine muscle can make it harder for an embryo to implant
  • Inflammation: An inflammatory environment in the uterus may reduce implantation success
  • Disrupted uterine contractions: Abnormal contractions may affect sperm movement or embryo positioning
  • Changes in the uterine lining: The endometrial environment may become less receptive to implantation

These factors can reduce the likelihood of successful implantation or early embryo development in some cases.

Signs and Symptoms to Watch For

Women who are trying to conceive should consider medical evaluation if they experience:
  • Heavy or prolonged menstrual bleeding
  • Severe menstrual cramps that worsen over time
  • Persistent pelvic pain or pressure
  • Abdominal bloating or a feeling of fullness in the lower abdomen
  • Pain during intercourse
These symptoms may indicate underlying uterine conditions, including adenomyosis, that could affect reproductive health.

How Is Adenomyosis Diagnosed?

Adenomyosis is typically diagnosed through a combination of clinical assessment and imaging tests.

  • Pelvic examination: May reveal an enlarged, tender uterus
  • Transvaginal ultrasound: Helps identify features such as a thickened uterine wall or small cysts
  • Magnetic resonance imaging (MRI): Provides more detailed images and is useful when the diagnosis is unclear

Treatment Options and Fertility Planning

Treatment for adenomyosis depends on symptom severity and whether a woman is planning to conceive.

  • Pain relief medication: To manage menstrual discomfort
  • Hormonal treatments: To control heavy bleeding and reduce symptoms
  • Fertility planning: Including assisted reproductive techniques such as IVF when needed

Care is typically tailored to balance symptom relief with the goal of preserving or improving fertility.

Supporting Your Fertility and Gynaecological Health

Adenomyosis may influence fertility in some women, but its impact can vary depending on the individual and the severity of the condition. With timely diagnosis and personalised care, many women can still achieve successful pregnancies.

Health & Fertility Centre for Women focuses on providing dedicated care for women’s fertility and gynaecological health. The clinic is led by Dr Kelly Loi, who draws upon her extensive experience in reproductive medicine and assisted fertility treatments when developing tailored management plans. Consult our specialist if you have symptoms or questions about conditions such as adenomyosis and to explore the appropriate treatment plans for your fertility concerns.

FAQs About Adenomyosis and Its Impact on Fertility

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